The First Sacrifice and the Last Sacrifice 

God slew the first sacrifice.
And God slew the last sacrifice.
The very first sacrifice took place before the foundation of the world.
That sacrifice was when God sacrificed His Son in His heart: “All who dwell on the earth will worship him, whose names have not been written in the Book of Life of the Lamb slain from the foundation of the world” (Revelation 13:8).
In human time, the first sacrifice in the Bible was when God slew an animal, shed its blood, and made coats of skins for Adam and Eve after they sinned (Genesis 3:21).
The last sacrifice was when God gave and sent His Son Jesus Christ to die for the world (Matthew 27:35-44, Mark 15:24-32, Luke 23:33-43, John 19:18-27).

God Clothes Adam and His Wife with Coats of Skins

“Also for Adam and his wife the Lord God made coats of skin, and clothed them” (Genesis 3:21, KJV). Other translations are “tunics/garments of skin.”
Genesis 3:21 reveals the eternal revelation of the sacrifice of Jesus Christ and the blood.
After Adam and Eve sinned, God covered them with the skins from the sacrifice of an animal and with blood.
God the Holy Spirit literally killed an animal, shed its blood, made garments of skin, and clothed Adam and Eve.
Out of His love and mercy, God performed acts so that He could now look upon Adam and Eve.

The Sacrifice of Jesus

God loves the world so much, that He gave His Son Jesus to die for the life of the world.
Jesus shed His blood seven times, to deliver mankind from the power of sin.
Jesus died on the cross so that man could receive eternal life and live forever with God in heaven.